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Case Studies
Project Overview
JNCK Bakery embarked on an 15-month Innovate UK-funded project, Nutritionally Enhanced, Sweet Bakery for All, aimed at developing HFSS-compliant, low-sugar bakery products. This initiative focused on reformulating popular baked goods while maintaining taste and texture, addressing the rising demand for healthier snack options. The project gained significant traction, leading to commercial partnerships with major retailers.
My Role as Monitoring Officer
As the Monitoring Officer, I played a pivotal role in ensuring the project stayed on track, adhered to compliance requirements, and maximised its potential. My responsibilities included overseeing risk mitigation strategies, optimising financial allocations, and supporting commercialisation efforts. Through structured oversight and regular intervention, I ensured that challenges were swiftly addressed.
Key Challenges and Solutions
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Prototype Development: Achieving HFSS compliance for muffins was difficult due to caramel and frosting formulations. I facilitated iterative improvements and resource reallocations.
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Manufacturing Scale-Up: Scaling up brownies for mass production required ingredient adjustments. I helped streamline alignment between developers and manufacturers.
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Packaging and Shelf-Life Optimisation: Engaged technical packaging consultants to enhance the shelf life and packaging design for broader retailer acceptance.
Key Achievements
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Successful Commercial Launch: HFSS-compliant cookies launched in 500+ Tesco stores, with additional product lines set for release.
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Optimised Production Efficiency: Addressed manufacturing bottlenecks, enhancing supply chain reliability.
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Retailer Partnerships: Expanded engagement with Tesco, Waitrose, and other major distributors.
Project Overview
Scarlet Therapeutics is pioneering bioengineered red blood cells (tRBCs) to treat metabolic disorders such as hyperammonemia and hyperoxaluria. The project aimed to establish a preclinical proof-of-concept to pave the way for clinical development and investor readiness.
My Role as Monitoring Officer
I played a crucial role in monitoring research progress, financial management, and commercialisation strategies. My oversight ensured that key milestones were met while managing technical risks effectively.
Key Challenges and Solutions
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Enzyme Performance at Neutral pH: Identified a strategic shift towards alternative enzyme solutions to maintain efficacy.
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Scope Adjustments & Budget Reallocation: Assisted in successfully submitting a PCR to reallocate underspent funds towards workforce expansion.
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Investor Readiness & IP Strategy: Advised on aggressive patent filings and investor engagement strategies to secure Series A funding.
Key Achievements
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Proof-of-Concept Demonstration: Established feasibility for ammonia reduction in preclinical models.
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Strategic Market Positioning: Strengthened IP portfolio and investor confidence through targeted outreach.
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Innovative Alternative Enzymes Identified: Implemented enzyme replacement strategies to mitigate metabolic inefficiencies.
Case Study:
Scarlet Therapeutics
Case Study:
MindSpire
Project Overview
MindSpire is an AI-driven mental health solution designed to improve early intervention through predictive modelling and personalised support strategies.
My Role as Monitoring Officer
I played a crucial role in monitoring research progress, financial I ensured that the project remained compliant, financially sound, and technically on track. My work included advising on commercial partnerships, regulatory considerations, and data security protocols., and commercialisation strategies. My oversight ensured that key milestones were met while managing technical risks effectively.
Case Study:
Mind Health AI
Project Overview
Mind Health AI developed CURB, an application using predictive behavioural science to help users manage harmful habits such as alcohol addiction.
My Role as Monitoring Officer
I played a key role in ensuring project compliance, assisting in budget reallocation, and refining the commercialisation strategy for broader market adoption.
Key Challenges and Solutions
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Financial Underspend: Helped optimise budget allocation towards key product enhancements.
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Commercialisation Strategy Refinement: Assisted in repositioning the app for expansion into nicotine and gambling addiction markets.
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Data Security & Compliance: Ensured regulatory alignment for NHS and international partnerships.
Key Achievements
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Successful App Launch: Over 345 early adopters with strong engagement metrics.
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Strategic Investment Growth: Secured NHS interest and a £750k seed funding pipeline.
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Expansion Into New Addictions: Positioned for broader B2B2C and direct-to-consumer applications.
Case Study:
Constructive Biology Ltd
Project Overview
Constructive Biology Ltd is developing a biomanufacturing platform to scale peptide drug production, addressing market shortages and sustainability concerns.
My Role as Monitoring Officer
I ensured technical, financial, and commercial oversight, guiding the project through scaling challenges and regulatory compliance.
Key Challenges and Solutions
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Scale-Up Risks: Encouraged phased scaling strategies to minimise production inefficiencies.
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PCR for Scope Adjustment: Assisted in modifying work package timelines for optimal research output.
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Financial Forecasting: Implemented improved tracking for accurate budget planning.
Key Achievements
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Lab-to-Pilot Transition Achieved: Successfully scaled production from 10-litre to 100-litre capacity.
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Pharma Partnerships Secured: Engaged industry leaders for long-term collaboration.
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Sustainability Metrics Established: Demonstrated an 8x reduction in waste output.
Case Study:
Tutti Toot
Project Overview
Tutti Toot developed a gamified respiratory training device for children with asthma, integrating digital tools for clinical monitoring and user engagement.
My Role as Monitoring Officer
I supported the team in refining commercialisation strategies, managing funding allocations, and ensuring compliance with NICE medical standards.
Key Challenges and Solutions
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Patient Recruitment Delays: Helped establish strategic partnerships for improved engagement.
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Cost Reallocation Needs: Assisted in shifting funds to maximise digital tool enhancements.
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Regulatory Preparation: Ensured compliance with NHS adoption criteria.
Key Achievements
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Successful Product Launch: Device and app completed with positive clinical trial feedback.
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Patents Secured: UK patent granted, with international applications in progress.
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Market Expansion Strategies Developed: Positioned for NHS and private sector integration.
Key Challenges and Solutions
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Data Limitations: Transitioned from wearable technology dependency to self-reported behavioural data, increasing scalability.
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Financial Variability: Assisted in reallocating resources to improve AI model robustness.
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Interdisciplinary Team Challenges: Implemented structured workflows to enhance collaboration and productivity.
Key Achievements
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Successful AI Model Development: Created a functional mental health predictive framework.
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Industry Partnerships Secured: Engaged leading research institutions and regulatory bodies.
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Expansion Strategy Established: Positioned for scaling across multiple healthcare applications.
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